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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-2-22
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pubmed:abstractText |
Controversy continues to surround the use of cyclooxygenase (COX)-2 inhibitors in the perioperative period. We designed this randomized, double-blind, placebo-controlled study to examine the hypothesis that administration of celecoxib preoperatively or postoperatively and for 3 days after major plastic surgery would improve pain control and clinically important patient outcomes. Another objective of the study was to determine whether perioperative administration of celecoxib offered any advantages over postoperative administration alone.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1526-7598
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
950-8, table of contents
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pubmed:meshHeading |
pubmed-meshheading:18292445-Activities of Daily Living,
pubmed-meshheading:18292445-Adult,
pubmed-meshheading:18292445-Analgesics, Opioid,
pubmed-meshheading:18292445-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:18292445-Defecation,
pubmed-meshheading:18292445-Double-Blind Method,
pubmed-meshheading:18292445-Drug Administration Schedule,
pubmed-meshheading:18292445-Female,
pubmed-meshheading:18292445-Gastrointestinal Motility,
pubmed-meshheading:18292445-Humans,
pubmed-meshheading:18292445-Male,
pubmed-meshheading:18292445-Middle Aged,
pubmed-meshheading:18292445-Morphine,
pubmed-meshheading:18292445-Pain, Postoperative,
pubmed-meshheading:18292445-Pain Measurement,
pubmed-meshheading:18292445-Patient Satisfaction,
pubmed-meshheading:18292445-Perioperative Care,
pubmed-meshheading:18292445-Postoperative Care,
pubmed-meshheading:18292445-Pyrazoles,
pubmed-meshheading:18292445-Reconstructive Surgical Procedures,
pubmed-meshheading:18292445-Sulfonamides,
pubmed-meshheading:18292445-Time Factors,
pubmed-meshheading:18292445-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Perioperative versus postoperative celecoxib on patient outcomes after major plastic surgery procedures.
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pubmed:affiliation |
Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9068, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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