Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-4-28
pubmed:abstractText
Four new purine alkaloids, namely, 6-(1'-purine-6',8'-dionyl)suberosanone ( 1), 3,9-(2-imino-1-methyl-4-imidazolidinone-5-yl)isopropenylpurine-6,8-dione ( 2), 1-(3'-carbonylbutyl)purine-6,8-dione ( 3), and 9-(3'-carbonylbutyl)purine-6,8-dione ( 4), together with three known compounds, guanosine ( 5), thymidine ( 6), and adenosine ( 7), were isolated from the EtOH/CH 2Cl 2 extracts of the South China Sea gorgonian Subergorgia suberosa. The structures of 1- 4 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR data. Compounds 1- 4 all showed weak cytotoxicity toward human cancer cell lines MDA-MB-231 and A435.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0163-3864
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
716-8
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Purine alkaloids from the South China Sea gorgonian Subergorgia suberosa.
pubmed:affiliation
Key Laboratory of Marine Bio-resourses Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangdong, People's Republic of China. shuhuaqi2001@yahoo.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't