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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-2-21
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pubmed:abstractText |
Brain-derived neurotrophic factor (BDNF) and its specific tryrosin kinase receptor-B (TrkB) are highly correlated to the chemoresistance of neuroblastoma (NB) cells and poor prognosis. This study observed the changes of the sensibility of NB cells to chemotherapy drug cisplatin (CDDP) before and after blockage of TrkB-BDNF signal pathway by specific tyrosin kinase inhibitor K252a.
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pubmed:language |
chi
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1008-8830
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-50
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18289471-Apoptosis,
pubmed-meshheading:18289471-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:18289471-Carbazoles,
pubmed-meshheading:18289471-Cell Line, Tumor,
pubmed-meshheading:18289471-Cisplatin,
pubmed-meshheading:18289471-Humans,
pubmed-meshheading:18289471-Indole Alkaloids,
pubmed-meshheading:18289471-Microscopy, Electron, Scanning,
pubmed-meshheading:18289471-Neuroblastoma,
pubmed-meshheading:18289471-Receptor, trkB,
pubmed-meshheading:18289471-Signal Transduction,
pubmed-meshheading:18289471-Tretinoin
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pubmed:year |
2008
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pubmed:articleTitle |
[Blocking TrkB-BDNF signal pathway decreases the livability of neuroblastoma cells].
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pubmed:affiliation |
Laboratory of Hematology, Second Affiliated Hospital of China Medical University, Shenyang 110004. zhangjihong_cmu@sina.com
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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