| pubmed-article:18289231 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18289231 | lifeskim:mentions | umls-concept:C0032961 | lld:lifeskim |
| pubmed-article:18289231 | lifeskim:mentions | umls-concept:C1261322 | lld:lifeskim |
| pubmed-article:18289231 | lifeskim:mentions | umls-concept:C0205463 | lld:lifeskim |
| pubmed-article:18289231 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18289231 | pubmed:dateCreated | 2008-2-21 | lld:pubmed |
| pubmed-article:18289231 | pubmed:abstractText | Hypoxaemia during anaesthetic induction in obstetrics is hazardous for mother and baby, but the onset of desaturation can be delayed by pre-oxygenation. This study investigated pre-oxygenation during pregnancy using computer simulation. The Nottingham Physiology Simulator was configured to replicate normal pregnant physiology. Three pregnant and three non-pregnant subjects were created, representing population variation according to published physiological values. They underwent pre-oxygenation by tidal and vital capacity breathing of 100% oxygen. Pre-oxygenation during tidal breathing proceeded more rapidly in pregnancy, the median [range] time to achieve 95% of the maximum change in P(E)O2 being 1 min 37 s [1:23-1:52] in pregnant subjects, compared to 2 min 51 s [2:28-3:15] in non-pregnant subjects. Vital capacity pre-oxygenation required seven breaths [5-10] in pregnant subjects, compared to six breaths [4-9] in non-pregnant subjects, to achieve the same P(E)O2 as after 95% complete tidal pre-oxygenation. We recommend 2 min of tidal breathing for pre-oxygenation in pregnancy. | lld:pubmed |
| pubmed-article:18289231 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18289231 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18289231 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18289231 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:18289231 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18289231 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18289231 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:18289231 | pubmed:issn | 1365-2044 | lld:pubmed |
| pubmed-article:18289231 | pubmed:author | pubmed-author:HardmanJ GJG | lld:pubmed |
| pubmed-article:18289231 | pubmed:author | pubmed-author:BogodD GDG | lld:pubmed |
| pubmed-article:18289231 | pubmed:author | pubmed-author:McClellandS... | lld:pubmed |
| pubmed-article:18289231 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18289231 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:18289231 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18289231 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18289231 | pubmed:pagination | 259-63 | lld:pubmed |
| pubmed-article:18289231 | pubmed:dateRevised | 2008-4-4 | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:meshHeading | pubmed-meshheading:18289231... | lld:pubmed |
| pubmed-article:18289231 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18289231 | pubmed:articleTitle | Pre-oxygenation in pregnancy: an investigation using physiological modelling. | lld:pubmed |
| pubmed-article:18289231 | pubmed:affiliation | Queen's Medical Centre campus, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham NG7 2UH, UK. | lld:pubmed |
| pubmed-article:18289231 | pubmed:publicationType | Journal Article | lld:pubmed |
