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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-7-19
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pubmed:abstractText |
To evaluate the expression of hepatocyte HLA Class I and II antigens and the infiltration of CD8-positive lymphocytes in patients with chronic hepatitis, cells obtained by the technique of fine-needle aspiration were compared with those obtained by percutaneous liver biopsy. In general, correlation between cytological and histological specimens of HLA Class I and Class II antigen expression and CD8 lymphocyte infiltration was excellent when comparing results of the core biopsy expressed semiquantitatively, and results from fine-needle aspiration quantitatively as percentage of cells stained. Although the major potential of multiple fine-needle aspiration sampling probably will be in the surveillance of patients who have received orthotopic liver transplants, the results of this study indicate that fine-needle aspiration can provide a useful technique for following antigen expression and inflammatory changes in studies in which frequent periodic samples may be necessary to monitor efficacy or toxicity of treatment regimens.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0168-8278
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
190-4
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:1828820-Biopsy,
pubmed-meshheading:1828820-Biopsy, Needle,
pubmed-meshheading:1828820-Chronic Disease,
pubmed-meshheading:1828820-HLA Antigens,
pubmed-meshheading:1828820-HLA-D Antigens,
pubmed-meshheading:1828820-Hepatitis, Viral, Human,
pubmed-meshheading:1828820-Histocompatibility Antigens Class I,
pubmed-meshheading:1828820-Humans,
pubmed-meshheading:1828820-Leukocyte Count,
pubmed-meshheading:1828820-T-Lymphocytes, Regulatory
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pubmed:year |
1991
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pubmed:articleTitle |
Expression of HLA antigens and T cell infiltrates in chronic viral hepatitis. A comparison of biopsy and fine-needle aspiration findings.
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pubmed:affiliation |
Hopital E. Herriot, INSERM U80, Lyon, France.
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pubmed:publicationType |
Journal Article
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