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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-7-9
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pubmed:abstractText |
Recent evidences suggest that Jun activation domain-binding protein 1 (Jab1) specifically interacts with the Cdk inhibitor p27kip1 and induces nuclear export and subsequent degradation of p27kip1. The purpose of this study is to investigate whether Jab1 expression is correlated with p27kip1 level in Non-Hodgkin's Lymphomas(NHLs) and how it influenced the stability of p27kip1, as well as whether Jab1 expression is associated with clinicopathologic variables and prognosis of NHLs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1555-8576
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
460-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18285702-Cell Survival,
pubmed-meshheading:18285702-Culture Media,
pubmed-meshheading:18285702-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:18285702-Female,
pubmed-meshheading:18285702-Homeostasis,
pubmed-meshheading:18285702-Humans,
pubmed-meshheading:18285702-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:18285702-Jurkat Cells,
pubmed-meshheading:18285702-Lymphoma, Non-Hodgkin,
pubmed-meshheading:18285702-Male,
pubmed-meshheading:18285702-Middle Aged,
pubmed-meshheading:18285702-Neoplasm Metastasis,
pubmed-meshheading:18285702-Neoplasm Staging,
pubmed-meshheading:18285702-Peptide Hydrolases
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pubmed:year |
2008
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pubmed:articleTitle |
Jun activation domain-binding protein 1 negatively regulate p27 kip1 in non-Hodgkin's lymphomas.
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pubmed:affiliation |
Department of Immunology and Microbiology, Medical College of Nantong University, Nantong, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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