|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
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|
pubmed:dateCreated |
2008-2-18
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|
pubmed:abstractText |
The phosphoinositide 3-kinase (PI3K)/Akt pathway is frequently activated in human cancer and plays a crucial role in neuroblastoma biology. We were interested in gaining further insight into the potential of targeting PI3K/Akt signaling as a novel antiproliferative approach in neuroblastoma.
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|
pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1078-0432
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
15
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1172-81
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|
pubmed:dateRevised |
2010-11-18
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|
pubmed:meshHeading |
pubmed-meshheading:18281552-Apoptosis,
pubmed-meshheading:18281552-Blotting, Western,
pubmed-meshheading:18281552-Cell Line, Tumor,
pubmed-meshheading:18281552-Cell Proliferation,
pubmed-meshheading:18281552-Cell Survival,
pubmed-meshheading:18281552-Cells, Cultured,
pubmed-meshheading:18281552-Gene Expression,
pubmed-meshheading:18281552-Gene Expression Profiling,
pubmed-meshheading:18281552-Humans,
pubmed-meshheading:18281552-Isoenzymes,
pubmed-meshheading:18281552-Neuroblastoma,
pubmed-meshheading:18281552-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:18281552-Protein Kinases,
pubmed-meshheading:18281552-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:18281552-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18281552-TOR Serine-Threonine Kinases
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.
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|
pubmed:affiliation |
Division of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
