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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-2-18
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pubmed:abstractText |
The ETV6 gene has been reported to be fused to a multitude of partner genes in various hematologic malignancies with 12p13 aberrations. Cytogenetic analysis of six cases of childhood acute lymphoblastic leukemia revealed a novel recurrent t(8;12)(q13;p13), suggesting involvement of ETV6.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ETS translocation variant 6 protein,
http://linkedlifedata.com/resource/pubmed/chemical/NCOA2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/NOTCH1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Receptor Coactivator 2,
http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Proteins, Fusion,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-ets,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Notch1,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:BieloraiBellaB,
pubmed-author:HaasOskar AOA,
pubmed-author:HarbottJochenJ,
pubmed-author:IzraeliShaiS,
pubmed-author:KönigMargitM,
pubmed-author:LessardMichelM,
pubmed-author:NebralKarinK,
pubmed-author:RateiRichardR,
pubmed-author:StrehlSabineS,
pubmed-author:StroblHerbertH,
pubmed-author:StruskiStephanieS,
pubmed-author:ZimmermannMartinM
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
977-83
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pubmed:meshHeading |
pubmed-meshheading:18281529-Adolescent,
pubmed-meshheading:18281529-Amino Acid Sequence,
pubmed-meshheading:18281529-Base Sequence,
pubmed-meshheading:18281529-Child,
pubmed-meshheading:18281529-Child, Preschool,
pubmed-meshheading:18281529-Female,
pubmed-meshheading:18281529-Humans,
pubmed-meshheading:18281529-Immunophenotyping,
pubmed-meshheading:18281529-In Situ Hybridization, Fluorescence,
pubmed-meshheading:18281529-Male,
pubmed-meshheading:18281529-Molecular Sequence Data,
pubmed-meshheading:18281529-Mutation,
pubmed-meshheading:18281529-Nuclear Receptor Coactivator 2,
pubmed-meshheading:18281529-Oncogene Fusion,
pubmed-meshheading:18281529-Oncogene Proteins, Fusion,
pubmed-meshheading:18281529-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:18281529-Proto-Oncogene Proteins c-ets,
pubmed-meshheading:18281529-Receptor, Notch1,
pubmed-meshheading:18281529-Repressor Proteins,
pubmed-meshheading:18281529-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2008
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pubmed:articleTitle |
ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations.
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pubmed:affiliation |
Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Kinderspitalgasse 6, A-1090 Vienna, Austria. sabine.strehl@ccri.at
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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