rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
3
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pubmed:dateCreated |
2008-2-18
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pubmed:abstractText |
Lichenoid graft-versus-host disease (liGVHD) histologically shares several common features with other lichenoid dermatoses, such as cutaneous lupus erythematosus and lichen planus (LP), which collectively show a junctional infiltrate of cytotoxic lymphocytes with liquefaction of the basal layer ("interface dermatitis"). Because recent studies have shown a role for type I interferon (IFN)-associated inflammation, including lymphocyte recruitment via CXCR3 <-> ligand interaction in cutaneous lupus erythematosus and LP, we hypothesized that similar mechanisms might also be involved in liGVHD.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CXCR3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL10,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL9,
http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR3,
http://linkedlifedata.com/resource/pubmed/chemical/myxovirus resistance proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
1097-6787
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
58
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
437-42
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pubmed:meshHeading |
pubmed-meshheading:18280341-Chemokine CXCL10,
pubmed-meshheading:18280341-Chemokine CXCL9,
pubmed-meshheading:18280341-Chronic Disease,
pubmed-meshheading:18280341-Dermatitis,
pubmed-meshheading:18280341-Epidermis,
pubmed-meshheading:18280341-GTP-Binding Proteins,
pubmed-meshheading:18280341-Graft vs Host Disease,
pubmed-meshheading:18280341-Humans,
pubmed-meshheading:18280341-In Situ Hybridization,
pubmed-meshheading:18280341-Interferon Type I,
pubmed-meshheading:18280341-Interferon-alpha,
pubmed-meshheading:18280341-Lichen Planus,
pubmed-meshheading:18280341-Lichenoid Eruptions,
pubmed-meshheading:18280341-Ligands,
pubmed-meshheading:18280341-Lymphocytes,
pubmed-meshheading:18280341-RNA, Messenger,
pubmed-meshheading:18280341-Receptors, CXCR3,
pubmed-meshheading:18280341-Skin Diseases,
pubmed-meshheading:18280341-T-Lymphocytes
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pubmed:year |
2008
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pubmed:articleTitle |
CXCR3 <-> ligand-mediated skin inflammation in cutaneous lichenoid graft-versus-host disease.
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pubmed:affiliation |
Department of Dermatology at the Universitie of Bonn, Bonn, Germany. joerg.wenzel@ukb.uni-bonn.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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