The -374T/A polymorphism of the Receptor for Advanced Glycation End products (RAGE) may exert a protective effect toward the development of atherosclerosis. No data are currently available on the potential prognostic role of this polymorphism in patients with angiographically proven coronary artery disease (CAD). Hereto we sought to address this issue in a large consecutive cohort of patients undergoing coronary revascularization.
Department of Cardiology, University Hospital Fondazione IRCCS San Matteo, Pavia, Italy; Interdepartmental Center for Research in Prevention of Cardiovascular and Metabolic Disorders (CIRMC), University of Pavia, Pavia, Italy.