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rdf:type |
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lifeskim:mentions |
umls-concept:C0030705,
umls-concept:C0032659,
umls-concept:C0178602,
umls-concept:C0201734,
umls-concept:C0246584,
umls-concept:C0376249,
umls-concept:C0746883,
umls-concept:C0936012,
umls-concept:C1527178,
umls-concept:C1705938,
umls-concept:C1709518
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-19
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pubmed:abstractText |
To establish a cefozopran (a fourth-generation cephem) population pharmacokinetic model using patient data and use it to explore alternative dosage regimens that could optimize the currently used dosing regimen to achieve higher likelihood of pharmacodynamic exposure against pathogenic bacteria.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1460-2091
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pubmed:author |
pubmed-author:FujimotoYoshikoY,
pubmed-author:FujitaNaohisaN,
pubmed-author:IkawaKazuroK,
pubmed-author:IkedaKayoK,
pubmed-author:KanbayashiYukoY,
pubmed-author:KomoriToshiakiT,
pubmed-author:MatsumotoYosukeY,
pubmed-author:MorikawaNorifumiN,
pubmed-author:NomuraKenichiK,
pubmed-author:ShimazakiChihiroC,
pubmed-author:ShimizuDaisukeD,
pubmed-author:ShimuraKazuhoK,
pubmed-author:TaniguchiKyokoK,
pubmed-author:TaniwakiMasafumiM
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pubmed:issnType |
Electronic
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
892-900
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pubmed:meshHeading |
pubmed-meshheading:18276604-Adult,
pubmed-meshheading:18276604-Aged,
pubmed-meshheading:18276604-Anti-Bacterial Agents,
pubmed-meshheading:18276604-Bacteria,
pubmed-meshheading:18276604-Bacterial Infections,
pubmed-meshheading:18276604-Cephalosporins,
pubmed-meshheading:18276604-Female,
pubmed-meshheading:18276604-Fever,
pubmed-meshheading:18276604-Hematologic Neoplasms,
pubmed-meshheading:18276604-Humans,
pubmed-meshheading:18276604-Male,
pubmed-meshheading:18276604-Microbial Sensitivity Tests,
pubmed-meshheading:18276604-Middle Aged,
pubmed-meshheading:18276604-Models, Statistical,
pubmed-meshheading:18276604-Monte Carlo Method,
pubmed-meshheading:18276604-Neutropenia,
pubmed-meshheading:18276604-Plasma
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pubmed:year |
2008
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pubmed:articleTitle |
Optimized dosage and frequency of cefozopran for patients with febrile neutropenia based on population pharmacokinetic and pharmacodynamic analysis.
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pubmed:affiliation |
Department of Haematology and Oncology, Kyoto Prefectural University of Medicine Graduate School of Medical Sciences, Kyoto, Japan. nomuken@koto.kpu-m.ac.jp
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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