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18276141
Source:
http://linkedlifedata.com/resource/pubmed/id/18276141
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rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0220781
,
umls-concept:C0243071
,
umls-concept:C1703326
,
umls-concept:C1883254
pubmed:issue
6
pubmed:dateCreated
2008-3-17
pubmed:abstractText
A series of 22-hydroxyacuminatine analogs was prepared by using different Friedländer condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/22-hydroxyacuminatine
,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents
,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Topoisomerases, Type I
,
http://linkedlifedata.com/resource/pubmed/chemical/Indolizines
,
http://linkedlifedata.com/resource/pubmed/chemical/Quinolines
,
http://linkedlifedata.com/resource/pubmed/chemical/Topoisomerase I Inhibitors
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1464-3405
pubmed:author
pubmed-author:BaumlováBarboraB
,
pubmed-author:BiggDennis C HDC
,
pubmed-author:ChaumeronSophieS
,
pubmed-author:ConstantJean-FrançoisJF
,
pubmed-author:GreeneAndrew EAE
,
pubmed-author:GrilletFrançoisF
,
pubmed-author:KanazawaAliceA
,
pubmed-author:PrévostGrégoireG
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2143-6
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:18276141-Antineoplastic Agents
,
pubmed-meshheading:18276141-DNA Topoisomerases, Type I
,
pubmed-meshheading:18276141-Humans
,
pubmed-meshheading:18276141-Indolizines
,
pubmed-meshheading:18276141-Molecular Structure
,
pubmed-meshheading:18276141-Neoplasms
,
pubmed-meshheading:18276141-Quinolines
,
pubmed-meshheading:18276141-Structure-Activity Relationship
,
pubmed-meshheading:18276141-Topoisomerase I Inhibitors
,
pubmed-meshheading:18276141-Tumor Cells, Cultured
pubmed:year
2008
pubmed:articleTitle
Synthesis and bioevaluation of 22-hydroxyacuminatine analogs.
pubmed:affiliation
Département de Chimie Moléculaire, UMR-5250, ICMG FR-2607, CNRS-Université Joseph Fourier, BP-53, 38041 Grenoble, France.
pubmed:publicationType
Journal Article
,
Research Support, Non-U.S. Gov't
,
Evaluation Studies