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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
Pt 1
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pubmed:dateCreated |
2008-2-15
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pubmed:abstractText |
Lamivudine (LAM)-resistant hepatitis B virus (HBV) with mutations in the polymerase region frequently appears after long-term use of LAM. Several methods allowing detection of mutant strains (YIDD, YVDD) have been reported, but they have no quantitative characteristics. In this study, we explored a unique approach for quantification of each mutant strain.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-5632
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pubmed:author |
pubmed-author:AsakaMasahiroM,
pubmed-author:ChibaHitoshiH,
pubmed-author:ChumaMakotoM,
pubmed-author:FujisawaShin-ichiS,
pubmed-author:HigeShuheiS,
pubmed-author:KitamuraTadashiroT,
pubmed-author:NishimuraMasaharuM,
pubmed-author:SatoKaoriK,
pubmed-author:YamashitaNaokiN,
pubmed-author:YoshidaMiyukiM,
pubmed-author:YoshidaShigeruS
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-64
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pubmed:meshHeading |
pubmed-meshheading:18275675-Base Sequence,
pubmed-meshheading:18275675-DNA Probes,
pubmed-meshheading:18275675-Drug Resistance, Viral,
pubmed-meshheading:18275675-Hepatitis B, Chronic,
pubmed-meshheading:18275675-Hepatitis B virus,
pubmed-meshheading:18275675-Humans,
pubmed-meshheading:18275675-Lamivudine,
pubmed-meshheading:18275675-Mutation,
pubmed-meshheading:18275675-Reproducibility of Results,
pubmed-meshheading:18275675-Sensitivity and Specificity,
pubmed-meshheading:18275675-Taq Polymerase
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pubmed:year |
2008
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pubmed:articleTitle |
Quantification of lamivudine-resistant hepatitis B virus mutants by type-specific TaqMan minor groove binder probe assay in patients with chronic hepatitis B.
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pubmed:affiliation |
Department of Health Sciences, Hokkaido University School of Medicine, North-12 West-5, Sapporo, Japan. shiyoshi@med.hokudai.ac.jp
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pubmed:publicationType |
Journal Article
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