Source:http://linkedlifedata.com/resource/pubmed/id/18261959
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-3-14
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pubmed:abstractText |
Recent discoveries involving the cytokine interleukin (IL)-6 have originated from diverse disciplines, revealing roles in biological processes that are likewise varied. The most novel findings suggest a connection between inflammation and diseases, such as insulin resistance associated with diabetes mellitus and cancer, which had not or only weakly been appreciated previously. The IL-6 pathway is one of the mechanisms linking inflammation to these disease processes. In addition, new evidence points toward IL-6 as one of the mediators coordinating the interface between adaptive and innate immunity. Here, we review the evidence linking IL-6 to inflammatory diseases and cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1471-4914
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
109-19
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18261959-Aging,
pubmed-meshheading:18261959-Animals,
pubmed-meshheading:18261959-Humans,
pubmed-meshheading:18261959-Immunity, Innate,
pubmed-meshheading:18261959-Inflammation,
pubmed-meshheading:18261959-Inflammatory Bowel Diseases,
pubmed-meshheading:18261959-Insulin Resistance,
pubmed-meshheading:18261959-Interleukin-6,
pubmed-meshheading:18261959-Mice,
pubmed-meshheading:18261959-Neoplasms,
pubmed-meshheading:18261959-Obesity,
pubmed-meshheading:18261959-Rheumatic Fever,
pubmed-meshheading:18261959-Signal Transduction
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pubmed:year |
2008
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pubmed:articleTitle |
The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer.
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pubmed:affiliation |
Department of Medicine, Division of Gastroenterology and Hepatology, Oregon Health and Sciences University, Portland, OR, USA.
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pubmed:publicationType |
Journal Article,
Review
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