| pubmed-article:18258425 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0006118 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0002520 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C0040399 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C1708632 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C1512628 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C1522485 | lld:lifeskim |
| pubmed-article:18258425 | lifeskim:mentions | umls-concept:C2353562 | lld:lifeskim |
| pubmed-article:18258425 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:18258425 | pubmed:dateCreated | 2008-2-18 | lld:pubmed |
| pubmed-article:18258425 | pubmed:abstractText | syn- and anti-1-amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic acid (syn-, anti-IVACBC 16, 17) and their analogue 1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid (gem-IVACBC 18) were synthesized and radioiodoinated with [(123)I] in 34-43% delay-corrected yield. All these amino acids entered 9L gliosarcoma cells primarily via L-type transport in vitro with high uptake of 8-10% ID/1 x 10(6) cells. Biodistribution studies of [(123)I]16, 17 and 18 in rats with 9L gliosarcoma brain tumors demonstrated high tumor to brain ratios (4.7-7.3:1 at 60 min post-injection). In this model, syn-, anti-, and gem-[(123)I]IVACBC are promising radiotracers for SPECT brain tumor imaging. | lld:pubmed |
| pubmed-article:18258425 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18258425 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18258425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18258425 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18258425 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:18258425 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:18258425 | pubmed:author | pubmed-author:OlsonJeffrey... | lld:pubmed |
| pubmed-article:18258425 | pubmed:author | pubmed-author:YuWeipingW | lld:pubmed |
| pubmed-article:18258425 | pubmed:author | pubmed-author:GoodmanMark... | lld:pubmed |
| pubmed-article:18258425 | pubmed:author | pubmed-author:CampVernon... | lld:pubmed |
| pubmed-article:18258425 | pubmed:author | pubmed-author:WilliamsLarry... | lld:pubmed |
| pubmed-article:18258425 | pubmed:author | pubmed-author:MalveauxEugen... | lld:pubmed |
| pubmed-article:18258425 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18258425 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:18258425 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:18258425 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18258425 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18258425 | pubmed:pagination | 1264-8 | lld:pubmed |
| pubmed-article:18258425 | pubmed:dateRevised | 2011-5-20 | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:meshHeading | pubmed-meshheading:18258425... | lld:pubmed |
| pubmed-article:18258425 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18258425 | pubmed:articleTitle | Synthesis and evaluation of [123I] labeled iodovinyl amino acids syn-, anti-1-amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic acid, and 1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid as potential SPECT brain tumor imaging agents. | lld:pubmed |
| pubmed-article:18258425 | pubmed:affiliation | Department of Radiology, Emory University, School of Medicine, Atlanta, GA 30322, USA. | lld:pubmed |
| pubmed-article:18258425 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18258425 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18258425 | lld:chembl |
