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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-22
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pubmed:abstractText |
We had previously established that inactivation of RUNX3 occurs by frequent promoter hypermethylation and protein mislocalization in invasive ductal carcinomas (IDC) of breast. Here, we hypothesize that inactivation of RUNX3 occurring in ductal carcinoma in situ (DCIS) represent early event in breast carcinogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1573-7217
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-21
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pubmed:meshHeading |
pubmed-meshheading:18256927-Breast Neoplasms,
pubmed-meshheading:18256927-Carcinoma, Ductal, Breast,
pubmed-meshheading:18256927-Carcinoma in Situ,
pubmed-meshheading:18256927-Core Binding Factor Alpha 3 Subunit,
pubmed-meshheading:18256927-DNA, Neoplasm,
pubmed-meshheading:18256927-DNA Methylation,
pubmed-meshheading:18256927-DNA Primers,
pubmed-meshheading:18256927-Disease Progression,
pubmed-meshheading:18256927-Female,
pubmed-meshheading:18256927-Humans,
pubmed-meshheading:18256927-Immunohistochemistry,
pubmed-meshheading:18256927-Mastectomy,
pubmed-meshheading:18256927-Microdissection,
pubmed-meshheading:18256927-Neoplasm Invasiveness,
pubmed-meshheading:18256927-Neoplasm Metastasis,
pubmed-meshheading:18256927-Polymerase Chain Reaction,
pubmed-meshheading:18256927-Promoter Regions, Genetic
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pubmed:year |
2009
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pubmed:articleTitle |
RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression.
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pubmed:affiliation |
Oncology Research Institute, National University of Singapore, Singapore, Republic of Singapore.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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