Linked Life Data

18253881

Source:http://linkedlifedata.com/resource/pubmed/id/18253881

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2008-2-6
pubmed:abstractText
The metatrophic fungus Paecilomyces sp. (Tree1-7) was isolated from an estuarine mangrove from the Taiwan Strait. The methanol extract of the fungal mycelium exhibited cytotoxicity against hepG2. Paeciloxanthone (1), a new xanthone, and the known compounds emodin (2) and chrysophanol (3), were isolated from the extract. Their structures were elucidated by spectroscopic experiments. Paeciloxanthone (1) exhibited in vitro cytotoxicity against hepG2 (IC(50)=1.08 microg/mL), acetylcholineesterase (AChE) inhibitory (IC(50)=2.25 microg/mL) and antimicrobial activities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1028-6020
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-7
pubmed:dateRevised
2009-7-21
pubmed:meshHeading
pubmed:articleTitle
Paeciloxanthone, a new cytotoxic xanthone from the marine mangrove fungus Paecilomyces sp. (Tree1-7).
pubmed:affiliation
School of Chemical and Chemical Engineering, and School of Pharmaceutical Science, Sun Yat-Sen (Zhongshan) University, Guangzhou, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't