|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013216,
umls-concept:C0017262,
umls-concept:C0023467,
umls-concept:C0185117,
umls-concept:C0376622,
umls-concept:C0870134,
umls-concept:C0871261,
umls-concept:C1426809,
umls-concept:C1704632,
umls-concept:C1704927,
umls-concept:C1704939,
umls-concept:C1706817,
umls-concept:C1823242,
umls-concept:C2911684,
umls-concept:C2911692
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2008-3-17
|
|
pubmed:abstractText |
Overexpression of members of the adenosine triphosphate binding cassette (ABC) transporter superfamily has been implicated in multidrug resistance in cancer, but results in acute myeloid leukemia (AML) have been inconsistent. We investigated the expression and activity of ABC transporters in patient total blasts and subpopulations along the leukemic stem cell hierarchy.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0301-472X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
36
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
433-42
|
|
pubmed:meshHeading |
pubmed-meshheading:18249061-ATP-Binding Cassette Transporters,
pubmed-meshheading:18249061-Adolescent,
pubmed-meshheading:18249061-Adult,
pubmed-meshheading:18249061-Aged,
pubmed-meshheading:18249061-Daunorubicin,
pubmed-meshheading:18249061-Dose-Response Relationship, Drug,
pubmed-meshheading:18249061-Drug Resistance, Neoplasm,
pubmed-meshheading:18249061-Female,
pubmed-meshheading:18249061-Flow Cytometry,
pubmed-meshheading:18249061-Humans,
pubmed-meshheading:18249061-Leukemia, Myeloid, Acute,
pubmed-meshheading:18249061-Male,
pubmed-meshheading:18249061-Middle Aged,
pubmed-meshheading:18249061-Neoplasm Proteins,
pubmed-meshheading:18249061-Neoplastic Stem Cells,
pubmed-meshheading:18249061-P-Glycoprotein,
pubmed-meshheading:18249061-Predictive Value of Tests,
pubmed-meshheading:18249061-RNA, Messenger,
pubmed-meshheading:18249061-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18249061-Tumor Cells, Cultured
|
|
pubmed:year |
2008
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|
pubmed:articleTitle |
MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia.
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|
pubmed:affiliation |
Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
