Source:http://linkedlifedata.com/resource/pubmed/id/18246075
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-2-29
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pubmed:abstractText |
Modern genetic analysis requires the development of new resources to systematically explore gene function in vivo. Overexpression screens are a powerful method to investigate genetic pathways, but the goal of routine and comprehensive overexpression screens has been hampered by the lack of systematic libraries. Here we describe the construction of a systematic collection of the Saccharomyces cerevisiae genome in a high-copy vector and its validation in two overexpression screens.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1548-7105
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-41
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pubmed:meshHeading |
pubmed-meshheading:18246075-Gene Expression Profiling,
pubmed-meshheading:18246075-Gene Expression Regulation, Fungal,
pubmed-meshheading:18246075-Gene Library,
pubmed-meshheading:18246075-Genes, Fungal,
pubmed-meshheading:18246075-Genome, Fungal,
pubmed-meshheading:18246075-Saccharomyces cerevisiae
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pubmed:year |
2008
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pubmed:articleTitle |
A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae.
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pubmed:affiliation |
Department of Molecular Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural,
Validation Studies
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