Linked Life Data

18246004

Source:http://linkedlifedata.com/resource/pubmed/id/18246004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
25
pubmed:dateCreated
2008-2-4
pubmed:abstractText
Human nucleus pulposus cells were cultured in alginate beads and activated with IL-1 beta or TNF-alpha, with and without inhibition of p38 mitogen activated protein kinase (p38 MAPK) activity. Cell production of factors modulating the anabolic/catabolic balance of the disc was determined.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/4-(4-fluorophenyl)-2-(4-hydroxypheny..., http://linkedlifedata.com/resource/pubmed/chemical/Alginates, http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Conditioned, http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone, http://linkedlifedata.com/resource/pubmed/chemical/Glucuronic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Hexuronic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1beta, http://linkedlifedata.com/resource/pubmed/chemical/MMP3 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide, http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Pyridines, http://linkedlifedata.com/resource/pubmed/chemical/Tissue Inhibitor of..., http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha, http://linkedlifedata.com/resource/pubmed/chemical/alginic acid, http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1528-1159
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2827-33
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:18246004-Adult, pubmed-meshheading:18246004-Alginates, pubmed-meshheading:18246004-Cell Culture Techniques, pubmed-meshheading:18246004-Cells, Cultured, pubmed-meshheading:18246004-Culture Media, Conditioned, pubmed-meshheading:18246004-Dinoprostone, pubmed-meshheading:18246004-Female, pubmed-meshheading:18246004-Glucuronic Acid, pubmed-meshheading:18246004-Hexuronic Acids, pubmed-meshheading:18246004-Humans, pubmed-meshheading:18246004-Imidazoles, pubmed-meshheading:18246004-Interleukin-1beta, pubmed-meshheading:18246004-Intervertebral Disc, pubmed-meshheading:18246004-Male, pubmed-meshheading:18246004-Matrix Metalloproteinase 3, pubmed-meshheading:18246004-Middle Aged, pubmed-meshheading:18246004-Nitric Oxide, pubmed-meshheading:18246004-Phosphorylation, pubmed-meshheading:18246004-Protein Kinase Inhibitors, pubmed-meshheading:18246004-Pyridines, pubmed-meshheading:18246004-Signal Transduction, pubmed-meshheading:18246004-Spinal Diseases, pubmed-meshheading:18246004-Time Factors, pubmed-meshheading:18246004-Tissue Inhibitor of Metalloproteinase-1, pubmed-meshheading:18246004-Tumor Necrosis Factor-alpha, pubmed-meshheading:18246004-p38 Mitogen-Activated Protein Kinases
pubmed:year
2007
pubmed:articleTitle
p38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degeneration.
pubmed:affiliation
VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA. rstuder@pitt.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural