Source:http://linkedlifedata.com/resource/pubmed/id/18245656
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2008-2-4
|
| pubmed:abstractText |
The glycocalyx is an important anti-inflammatory and anti-adhesive barrier at the luminal side of endothelial cells. Glycocalyx volume was significantly reduced in sickle cell patients (HbSS/HbSbeta(0)-thalassemia median 0.47L, IQR 0.27-0.66, HbSC/HbSbeta(+)-thalassemia 0.23L, 0.0-0.58) compared with controls (1 x 10(9)L, 0.52-1.77) (p=0.03). Reduced glycocalyx may be a new factor in the pathophysiology of sickle cell disease.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1592-8721
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
93
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
307-8
|
| pubmed:meshHeading | |
| pubmed:year |
2008
|
| pubmed:articleTitle |
Sickle cell patients are characterized by a reduced glycocalyx volume.
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| pubmed:publicationType |
Letter
|