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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-2-4
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pubmed:abstractText |
Connexin 26 (Cx26) is one of the gap junction-forming family members classically considered to be tumor suppressors. However, recent studies show association of elevated expression of Cx26 with poor prognosis in several human malignancies. Furthermore, Cx26 has been observed to be indispensable to spontaneous metastasis of melanoma cells. Here, we assessed Cx26 expression in primary colorectal cancer (CRC) and the metastatic lesions to elucidate its role in metastasis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:DamdinsurenBazarragchaaB,
pubmed-author:EzumiKojiK,
pubmed-author:HigashiyamaMasahikoM,
pubmed-author:IkedaMasatakaM,
pubmed-author:KyoNaganoriN,
pubmed-author:MatsuuraNariakiN,
pubmed-author:MondenMoritoM,
pubmed-author:MurataKoheiK,
pubmed-author:NakamuraYurikaY,
pubmed-author:NganChew YeeCY,
pubmed-author:NojimaHiroshiH,
pubmed-author:OkamiJiroJ,
pubmed-author:SekimotoMitsuguM,
pubmed-author:TakemasaIchiroI,
pubmed-author:YamamotoHirofumiH
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
677-84
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pubmed:meshHeading |
pubmed-meshheading:18245526-Adult,
pubmed-meshheading:18245526-Aged,
pubmed-meshheading:18245526-Aged, 80 and over,
pubmed-meshheading:18245526-Colorectal Neoplasms,
pubmed-meshheading:18245526-Connexins,
pubmed-meshheading:18245526-DNA Primers,
pubmed-meshheading:18245526-Female,
pubmed-meshheading:18245526-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18245526-Humans,
pubmed-meshheading:18245526-Immunohistochemistry,
pubmed-meshheading:18245526-Intestinal Mucosa,
pubmed-meshheading:18245526-Lung Neoplasms,
pubmed-meshheading:18245526-Male,
pubmed-meshheading:18245526-Middle Aged,
pubmed-meshheading:18245526-Neoplasm Metastasis,
pubmed-meshheading:18245526-Polymerase Chain Reaction
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pubmed:year |
2008
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pubmed:articleTitle |
Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer.
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pubmed:affiliation |
Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Yamada-oka, Suita City, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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