Linked Life Data

1824540

Source:http://linkedlifedata.com/resource/pubmed/id/1824540

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1992-10-22
pubmed:abstractText
Groups of each 8 male Long-Evans rats were treated with 1 or 10 micrograms/kg LHRH intraperitoneally and compared with control rats which received the vehicle fluid (NaCl-solution). Ambulatory activity in an open field (OF), entrance to central fields and the mobility index were significantly decreased by both doses. Correspondingly, wheel running and movement velocity were significantly decreased. A further group of 8 rats with chronically implanted electrodes which was habituated to sessions showed an increase of slow-wave sleep and a significant reduction of waking and active states with maximal expression 45 min after ip application of 10 micrograms/kg LHRH. Paradoxical sleep was slightly reduced. Sleep-wakefulness cyclograms showed increase of a sleep phase duration to 175% and of single slow wave sleep phase duration to 140% after LHRH. Phases of drowsiness were also prolonged.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1225-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Systemically applied luteinizing hormone-releasing hormone (LHRH) reduces behavioural activity in rats and increases sleep activity.
pubmed:affiliation
Paul Flechsig Institute for Brain Research, Department of Neurophysiology of the University, Leipzig, Germany.
pubmed:publicationType
Journal Article