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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-8-19
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pubmed:abstractText |
Early growth response factor-1 (Egr-1) controls the gene expression involved in postangioplasty restenosis. In the present study we synthesized specific catalytic DNA targeting sequences in human Egr-1 mRNA to investigate the effects on artery balloon injury.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1874-1754
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
16
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
118-24
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18242730-Animals,
pubmed-meshheading:18242730-Balloon Dilation,
pubmed-meshheading:18242730-Catalysis,
pubmed-meshheading:18242730-DNA, Single-Stranded,
pubmed-meshheading:18242730-Early Growth Response Protein 1,
pubmed-meshheading:18242730-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:18242730-Hyperplasia,
pubmed-meshheading:18242730-Male,
pubmed-meshheading:18242730-Rats,
pubmed-meshheading:18242730-Rats, Wistar,
pubmed-meshheading:18242730-Transfection,
pubmed-meshheading:18242730-Tunica Intima
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pubmed:year |
2008
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pubmed:articleTitle |
Transfected synthetic DNA enzyme gene specifically inhibits Egr-1 gene expression and reduces neointimal hyperplasia following balloon injury in rats.
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pubmed:affiliation |
Department of Cardiology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China. guinanliu@hotmail.com
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pubmed:publicationType |
Journal Article,
Comparative Study
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