Source:http://linkedlifedata.com/resource/pubmed/id/18239872
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2008-2-1
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| pubmed:abstractText |
Adenomyoepithelioma is an uncommon primary breast tumor. It is conspicuous for two elements of the tumor, namely, ductal and myoepithelial components. Recently, a Mammotome biopsy, or stereotactic vacuum-assisted biopsy has become popular and various benign or borderline lesions are obtained. We report an adenomyoepithelioma of the breast in a 56-year-old woman. She was pointed out to have a cluster of some microcalcifications on mammography and a 9-mm hypoechoic mass lesion was detected by ultrasound. A Mammotome biopsy revealed a well-defined lesion. Histologically, the tumor demonstrated a thick and bi-cellular growth pattern consisting of ducts and myoepithelium. Immunohistochemically, epithelial cells were positive for cytokeratin AE1/AE3 and cytokeratin, epithelial membrane antigen (EMA), and carcinoembryonic antigen (CEA), negative for alpha-smooth muscle actin (alpha-SMA). In addition, myoepithelial cells were positive for alpha-SMA and CEA, which were scatterly positive for cytokeratin AE1/AE3, and negative for EMA. In examinations of non-palpable lesions found on mammography and ultrasound, a Mammotome biopsy is useful for making diagnosis, however, and adenomyoepithelioma is rarely found. In diagnosing such a rare disease from the limited information obtained from a needle biopsy, an immunohistochemical study was thus found to be useful for making a differential diagnosis.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:issn |
0941-1291
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
38
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
144-6
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| pubmed:meshHeading |
pubmed-meshheading:18239872-Adenomyoma,
pubmed-meshheading:18239872-Biopsy, Needle,
pubmed-meshheading:18239872-Breast Neoplasms,
pubmed-meshheading:18239872-Calcinosis,
pubmed-meshheading:18239872-Female,
pubmed-meshheading:18239872-Humans,
pubmed-meshheading:18239872-Middle Aged,
pubmed-meshheading:18239872-Myoepithelioma,
pubmed-meshheading:18239872-Stereotaxic Techniques
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| pubmed:year |
2008
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| pubmed:articleTitle |
Adenomyoepithelioma of the breast diagnosed by a mammotome biopsy: report of a case.
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| pubmed:affiliation |
Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan.
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| pubmed:publicationType |
Journal Article
|