Linked Life Data

1823622

Source:http://linkedlifedata.com/resource/pubmed/id/1823622

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-9-25
pubmed:abstractText
Conformational energy maps and descriptions of structures at the local minima are presented for the following fragments found in N-acetyllactosaminic type glycans of N-glycoproteins: GlcNAc beta(1-2)Man, GlcNAc beta(1-4)Man, GlcNAc beta(1-6)Man, Gal beta(1-4)GlcNAc, GlcNAc beta(1-3)Gal, Fuc alpha(1-6)GlcNAc, Fuc alpha(1-3)GlcNAc, Xyl beta(1-2)Man, Gal beta(1-3)GlcNAc and GlcNAc beta(1-6)Gal. These results are the second part of a data bank on glycoprotein moieties; five disaccharides found in oligomannose type N-glycans were analysed earlier (Imberty et al., 1990, Glycoconjugate J 7:27-54). In the present study, three to seven minima are found for each dimer. Conformations of disaccharide fragments found in the crystal structure of the complex of a biantennary octasaccharide with Lathyrus ochrus lectin are plotted on these energy maps. While the observed conformations are at predicted minima, they are not always at the minimum predicted to have the lowest energy. Further, not all observed conformations are stabilized by the exo-anomeric effect. We conclude that these oligosaccharides are highly flexible.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0282-0080
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
456-83
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Data bank of three-dimensional structures of disaccharides: Part II, N-acetyllactosaminic type N-glycans. Comparison with the crystal structure of a biantennary octasaccharide.
pubmed:affiliation
Laboratoire de Synthèse Organique, Faculté des Sciences, Nantes, France.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't