Source:http://linkedlifedata.com/resource/pubmed/id/18232020
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-3-18
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pubmed:abstractText |
Acetaminophen (APAP) use in early pregnancy has been associated with the risk of gastroschisis, a rare but serious congenital defect of the abdominal wall. The purpose of this study was to characterize the variability of APAP sulfation in a panel of human fetal livers and to identify the sulfotransferases (SULT) isoform(s) responsible for catalyzing that activity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1542-0760
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2007 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
155-65
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pubmed:meshHeading |
pubmed-meshheading:18232020-Abnormalities, Drug-Induced,
pubmed-meshheading:18232020-Acetaminophen,
pubmed-meshheading:18232020-Humans,
pubmed-meshheading:18232020-Liver,
pubmed-meshheading:18232020-Pharmacogenetics,
pubmed-meshheading:18232020-Sulfates,
pubmed-meshheading:18232020-Sulfotransferases
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pubmed:year |
2008
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pubmed:articleTitle |
Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects.
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pubmed:affiliation |
Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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