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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-2-4
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pubmed:abstractText |
Four different patterns of demyelination have been described in active demyelinating lesions of multiple sclerosis (MS) patients that were biopsied shortly after disease onset. These patterns were suggested to represent heterogeneity of the underlying pathogenesis. The aim of this study was to determine whether lesion heterogeneity also exists in an unselected collection of autopsy material from patients with established MS.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1531-8249
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16-25
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pubmed:meshHeading |
pubmed-meshheading:18232012-Adult,
pubmed-meshheading:18232012-Aged,
pubmed-meshheading:18232012-Apoptosis,
pubmed-meshheading:18232012-Autoantibodies,
pubmed-meshheading:18232012-Autoantigens,
pubmed-meshheading:18232012-Autoimmunity,
pubmed-meshheading:18232012-Autopsy,
pubmed-meshheading:18232012-Biological Markers,
pubmed-meshheading:18232012-Central Nervous System,
pubmed-meshheading:18232012-Complement Activation,
pubmed-meshheading:18232012-Complement System Proteins,
pubmed-meshheading:18232012-Disease Progression,
pubmed-meshheading:18232012-Female,
pubmed-meshheading:18232012-Humans,
pubmed-meshheading:18232012-Immunoglobulin G,
pubmed-meshheading:18232012-Macrophages,
pubmed-meshheading:18232012-Magnetic Resonance Imaging,
pubmed-meshheading:18232012-Male,
pubmed-meshheading:18232012-Middle Aged,
pubmed-meshheading:18232012-Multiple Sclerosis,
pubmed-meshheading:18232012-Myelin-Associated Glycoprotein,
pubmed-meshheading:18232012-Nerve Fibers, Myelinated,
pubmed-meshheading:18232012-Oligodendroglia
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pubmed:year |
2008
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pubmed:articleTitle |
Homogeneity of active demyelinating lesions in established multiple sclerosis.
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pubmed:affiliation |
Department of Molecular Cell Biology and Immunology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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