The involvement of respiratory muscles is a major predicting factor for survival in amyotrophic lateral sclerosis (ALS). Recent studies show that noninvasive ventilation (NIV) can relieve symptoms of alveolar hypoventilation. However, factors predicting survival in ALS patients when treated with NIV need to be clarified.
Faculté de Médecine Lyon Sud, Université Lyon 1, et Centre SLA, Hôpital Neurologique et Neurochirurgical, Hospices Civils de Lyon, Lyon, France. stephane.peysson@chu-lyon.fr