Source:http://linkedlifedata.com/resource/pubmed/id/18230277
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-1-30
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pubmed:abstractText |
We investigated the effects of high-monounsaturated fatty acid (MUFA) versus high-carbohydrate enteral formula on post-prandial plasma glucose concentration and insulin response in Japanese patients with type 2 diabetes mellitus and healthy Japanese volunteers. Ten healthy volunteers aged 20.8 +/- 1.2 years and 12 diabetic patients with good glycaemic control (glycosylated haemoglobulin < 7%) aged 58.6 +/- 7.7 years were randomly assigned to take high-MUFA or high-carbohydrate formula after a 12-h overnight fast. The patients switched to the other formula after 7 days. Post-prandial plasma glucose and insulin response were significantly lower in all subjects after taking high-MUFA formula compared with high-carbohydrate formula. No differences were observed in free fatty acids, triglycerides and plasma glucagon between the two diet groups. In conclusion, a high-MUFA enteral formula suppresses post-prandial hyperglycaemia without exaggerated insulin secretion compared with a high-carbohydrate enteral diet in patients with type 2 diabetes and healthy subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Carbohydrates,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Monounsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Nonesterified,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Hemoglobin A, Glycosylated,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-0605
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
137-46
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18230277-Adult,
pubmed-meshheading:18230277-Blood Glucose,
pubmed-meshheading:18230277-Diabetes Mellitus, Type 2,
pubmed-meshheading:18230277-Dietary Carbohydrates,
pubmed-meshheading:18230277-Enteral Nutrition,
pubmed-meshheading:18230277-Fatty Acids, Monounsaturated,
pubmed-meshheading:18230277-Fatty Acids, Nonesterified,
pubmed-meshheading:18230277-Female,
pubmed-meshheading:18230277-Glucagon,
pubmed-meshheading:18230277-Hemoglobin A, Glycosylated,
pubmed-meshheading:18230277-Humans,
pubmed-meshheading:18230277-Insulin,
pubmed-meshheading:18230277-Male,
pubmed-meshheading:18230277-Middle Aged,
pubmed-meshheading:18230277-Triglycerides
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pubmed:articleTitle |
Effects of high-monounsaturated fatty acid enteral formula versus high-carbohydrate enteral formula on plasma glucose concentration and insulin secretion in healthy individuals and diabetic patients.
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pubmed:affiliation |
Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei Daisan University Hospital, Komae City, Tokyo, Japan. jyoko@jikei.ac.jp
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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