Linked Life Data

1822832

Source:http://linkedlifedata.com/resource/pubmed/id/1822832

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1992-9-10
pubmed:abstractText
The effects of prednisolone, salbutamol or theophylline treatment were studied in guinea pigs on bronchial hyperreactivity induced by chronic administration of PAF, (subsequently measuring respiratory flow after an intravenous injection of histamine) and the chemokinesis of leucocytes in vitro. Prednisolone (10 mg/kg p.o.) was active in the bronchial hyperreactivity test, as was salbutamol, but its effect appeared to be more related to its bronchodilator activity per se, while theophylline had little activity in this test. Regarding leucocyte chemokinetic activity, prednisolone and theophylline inhibited this at nM and microM concentrations respectively, whereas salbutamol was weakly active in this test.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-6501
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
395-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Effects of prednisolone, salbutamol and theophylline on bronchial hyperreactivity and leucocyte chemokinesis in guinea pigs.
pubmed:affiliation
Division of Biological Sciences, Laboratorios Almirall, Barcelona, Spain.
pubmed:publicationType
Journal Article, Comparative Study