Linked Life Data

18227999

Source:http://linkedlifedata.com/resource/pubmed/id/18227999

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-3-24
pubmed:abstractText
The development and progression of severe sepsis is related to a deficiency in pro-inflammatory cytokine production, characterised by lesser IFNgamma levels, which are not explained by variations in levels of the main putative regulator of IFNgamma, namely IL-12. As alternative regulators of IFNgamma may be of greater importance in human sepsis, we investigated the hypothesis that the development of severe sepsis is related to variations in IL-18, IL-23 and IL-27 gene expression.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0342-4642
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
683-91
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:18227999-Adult, pubmed-meshheading:18227999-Aged, pubmed-meshheading:18227999-Aged, 80 and over, pubmed-meshheading:18227999-Bacteremia, pubmed-meshheading:18227999-Case-Control Studies, pubmed-meshheading:18227999-Disease Progression, pubmed-meshheading:18227999-Female, pubmed-meshheading:18227999-Gene Expression Regulation, pubmed-meshheading:18227999-Humans, pubmed-meshheading:18227999-Interferon-gamma, pubmed-meshheading:18227999-Interleukin-17, pubmed-meshheading:18227999-Interleukin-18, pubmed-meshheading:18227999-Interleukin-23, pubmed-meshheading:18227999-Male, pubmed-meshheading:18227999-Middle Aged, pubmed-meshheading:18227999-Prospective Studies, pubmed-meshheading:18227999-RNA, Messenger, pubmed-meshheading:18227999-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:18227999-Survival Analysis, pubmed-meshheading:18227999-Systemic Inflammatory Response Syndrome
pubmed:year
2008
pubmed:articleTitle
The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression.
pubmed:affiliation
Department of Anaesthesia, St James's Hospital, Dublin, Ireland.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't