Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-9-10
pubmed:abstractText
While subplate neurons are lost in the development of the cerebral cortex of other mammalian species that have so far been investigated, in rodents the subplate (alternately termed layer VIb or VII) persists to adulthood, at least in part. We traced the developmental course of the subplate in the golden hamster, using two methods. We first used tritiated thymidine labeling to trace relative changes in the numbers of identified cohorts of cells in the subplate, layer VI, and the LGN. We also estimated the total number of cells in the subplate versus layer VI of the cortex from early in development to adulthood. These methods showed a high rate of cell loss in the subplate, between 50% and 80%, but with the clear retention of a substantial fraction of this early-generated population as a recognizable layer in adulthood. Species variations in the timing of cortical neurogenesis and the relative amount of cell loss in the subplate can be used to better describe the developmental function of this region.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1047-3211
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
433-43
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Dual fate of subplate neurons in a rodent.
pubmed:affiliation
Department of Psychology, Cornell University, Ithaca, New York 14853.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.