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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-1-29
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pubmed:abstractText |
Although homocysteine (HCY) is a risk factor for cardiovascular diseases, recent clinical trials failed to show the benefits by reducing plasma HCY. Alternative strategy with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, statins, might be feasible. This study investigated HCY-induced endothelial adhesiveness with mononuclear cells (MNCs) from patients with coronary artery disease (CAD). The direct endothelial protective effects of statins were also examined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1365-2362
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
106-16
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pubmed:meshHeading |
pubmed-meshheading:18226044-Aged,
pubmed-meshheading:18226044-Anticholesteremic Agents,
pubmed-meshheading:18226044-Case-Control Studies,
pubmed-meshheading:18226044-Cell Adhesion,
pubmed-meshheading:18226044-Cell Adhesion Molecules,
pubmed-meshheading:18226044-Coronary Artery Disease,
pubmed-meshheading:18226044-Endothelial Cells,
pubmed-meshheading:18226044-Endothelium, Vascular,
pubmed-meshheading:18226044-Female,
pubmed-meshheading:18226044-Homocysteine,
pubmed-meshheading:18226044-Humans,
pubmed-meshheading:18226044-Male,
pubmed-meshheading:18226044-Middle Aged,
pubmed-meshheading:18226044-Pravastatin,
pubmed-meshheading:18226044-Simvastatin
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pubmed:year |
2008
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pubmed:articleTitle |
Direct effect of statins on homocysteine-induced endothelial adhesiveness: potential impact to human atherosclerosis.
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pubmed:affiliation |
Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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