Linked Life Data

18226030

Source:http://linkedlifedata.com/resource/pubmed/id/18226030

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-1-29
pubmed:abstractText
Children with congenital or acquired atrioventricular block are provided with ventricular rate support from a pacing lead that traditionally is positioned at the right ventricular (RV) apex. However, RV apical pacing causes dyssynchronous electrical activation and left ventricular (LV) contraction, resulting in decreased LV function. Chronic RV apical pacing leads to deterioration of LV function and morphology, resulting in cardiac failure in approximately 7% of children. This review describes the pathophysiology of pacing-induced dyssynchronous LV activation and contraction, especially as a result of chronic RV apical pacing. Furthermore, this review provides an overview of the possible alternative pacing sites, such as the RV outflow tract, His-bundle, LV apex, and biventricular pacing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1540-8159
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
31 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S24-7
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Physiology of cardiac pacing in children: the importance of the ventricular pacing site.
pubmed:affiliation
Departments of Physiology, and Pediatrics, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Review