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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-1-29
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pubmed:abstractText |
Expression of genes for redox-dependent glutathione S-transferase isoforms GSTP1-1 and GSTA4-4 in tumor cells K562, MCF-7, and SKOV-3 was studied during the development of resistance to doxorubicin. It was found that the development of resistance was accompanied by predominant increase in the expression of hGSTP1 gene in MCF-7 cells, and hGSTA4 gene in resistant K562/DOX and SKVLB cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin,
http://linkedlifedata.com/resource/pubmed/chemical/GSTP1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione S-Transferase pi,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Transferase,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/leukotriene-C4 synthase
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0007-4888
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
143
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
328-30
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pubmed:meshHeading |
pubmed-meshheading:18225754-Base Sequence,
pubmed-meshheading:18225754-Breast Neoplasms,
pubmed-meshheading:18225754-Cell Line, Tumor,
pubmed-meshheading:18225754-DNA Primers,
pubmed-meshheading:18225754-Doxorubicin,
pubmed-meshheading:18225754-Drug Resistance, Neoplasm,
pubmed-meshheading:18225754-Female,
pubmed-meshheading:18225754-Gene Expression,
pubmed-meshheading:18225754-Glutathione S-Transferase pi,
pubmed-meshheading:18225754-Glutathione Transferase,
pubmed-meshheading:18225754-Humans,
pubmed-meshheading:18225754-K562 Cells,
pubmed-meshheading:18225754-Neoplasms,
pubmed-meshheading:18225754-Ovarian Neoplasms,
pubmed-meshheading:18225754-RNA, Messenger,
pubmed-meshheading:18225754-RNA, Neoplasm
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pubmed:year |
2007
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pubmed:articleTitle |
Expression of genes for redox-dependent glutathione S-transferase isoforms GSTP1-1 and GSTA4-4 in tumor cell during the development doxorubicin resistance.
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pubmed:affiliation |
Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow. kevsan@orc.ru
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pubmed:publicationType |
Journal Article
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