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rdf:type |
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lifeskim:mentions |
umls-concept:C0005953,
umls-concept:C0023473,
umls-concept:C0032520,
umls-concept:C0162789,
umls-concept:C0175659,
umls-concept:C0222045,
umls-concept:C0229664,
umls-concept:C0349674,
umls-concept:C0392762,
umls-concept:C0543478,
umls-concept:C0812425,
umls-concept:C1512888,
umls-concept:C1550177,
umls-concept:C1621812,
umls-concept:C1707455
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pubmed:issue |
2
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pubmed:dateCreated |
2008-2-4
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pubmed:abstractText |
Recently, an International Scale was proposed for standardizing BCR-ABL transcript measurements and reporting in the assessment of minimal residual disease by real-time quantitative polymerase chain reaction (RQ-PCR). Here we present the setting up of the International Scale conversion factors for a national laboratory by performing both a cross-analysis of a set of standard samples from a reference laboratory and an analysis of bone marrow and peripheral blood samples at diagnosis (from 32 and 27 patients, respectively).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1592-8721
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
178-85
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pubmed:meshHeading |
pubmed-meshheading:18223279-Bone Marrow,
pubmed-meshheading:18223279-Female,
pubmed-meshheading:18223279-Follow-Up Studies,
pubmed-meshheading:18223279-Fusion Proteins, bcr-abl,
pubmed-meshheading:18223279-Humans,
pubmed-meshheading:18223279-In Situ Hybridization, Fluorescence,
pubmed-meshheading:18223279-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:18223279-Leukocytes, Mononuclear,
pubmed-meshheading:18223279-Male,
pubmed-meshheading:18223279-Metaphase,
pubmed-meshheading:18223279-Mitotic Index,
pubmed-meshheading:18223279-Neoplasm, Residual,
pubmed-meshheading:18223279-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2008
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pubmed:articleTitle |
Comparison of bone marrow high mitotic index metaphase fluorescence in situ hybridization to peripheral blood and bone marrow real time quantitative polymerase chain reaction on the International Scale for detecting residual disease in chronic myeloid leukemia.
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pubmed:affiliation |
Department of Pathology, Laboratory of Molecular Pathology, Haartman Institute and HUSLAB, Helsinki, Finland.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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