Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-3-10
pubmed:abstractText
Matrix metalloproteinases (MMPs), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) are mediators of liver regeneration. To determine whether MMPs are required for normal hepatic regeneration, we performed 67% hepatectomies on mice treated with a broad-spectrum MMP-inhibitor, and assessed the effect on liver regeneration and urinary MMP activity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
145
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
192-8
pubmed:meshHeading
pubmed-meshheading:18222481-Animals, pubmed-meshheading:18222481-Body Weight, pubmed-meshheading:18222481-Enzyme Inhibitors, pubmed-meshheading:18222481-Hepatectomy, pubmed-meshheading:18222481-Hepatocyte Growth Factor, pubmed-meshheading:18222481-Hydroxamic Acids, pubmed-meshheading:18222481-Interleukin-6, pubmed-meshheading:18222481-Liver, pubmed-meshheading:18222481-Liver Function Tests, pubmed-meshheading:18222481-Liver Regeneration, pubmed-meshheading:18222481-Male, pubmed-meshheading:18222481-Matrix Metalloproteinase 2, pubmed-meshheading:18222481-Matrix Metalloproteinase 9, pubmed-meshheading:18222481-Mice, pubmed-meshheading:18222481-Mice, Inbred C57BL, pubmed-meshheading:18222481-Microcirculation, pubmed-meshheading:18222481-Organ Size, pubmed-meshheading:18222481-Receptors, Tumor Necrosis Factor, Type II, pubmed-meshheading:18222481-Tumor Necrosis Factor-alpha
pubmed:year
2008
pubmed:articleTitle
A critical role for matrix metalloproteinases in liver regeneration.
pubmed:affiliation
Department of Surgery and The Vascular Biology Program, Children's Hospital, Boston, Massachusetts 02115, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural