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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0017710,
umls-concept:C0020456,
umls-concept:C0020557,
umls-concept:C0023822,
umls-concept:C0030705,
umls-concept:C0086860,
umls-concept:C0205216,
umls-concept:C0332281,
umls-concept:C0559956,
umls-concept:C0729627,
umls-concept:C1413353,
umls-concept:C1882417
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pubmed:issue |
3
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pubmed:dateCreated |
2008-10-17
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pubmed:abstractText |
The effect of glucocorticoid substitution on the prevalence of metabolic syndrome components (NCEP ATP III criteria) and serum lipid levels was determined in GH-replaced hypopituitary patients. As glucocorticoid replacement is associated with a pronounced decrease in plasma cholesteryl ester transfer protein (CETP) activity, we also tested associations of HDL cholesterol with the -629C>A CETP promoter polymorphism in subjects with and without ACTH deficiency.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1365-2265
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
359-66
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18221399-Adolescent,
pubmed-meshheading:18221399-Adult,
pubmed-meshheading:18221399-Aged,
pubmed-meshheading:18221399-Blood Glucose,
pubmed-meshheading:18221399-Cholesterol,
pubmed-meshheading:18221399-Cholesterol Ester Transfer Proteins,
pubmed-meshheading:18221399-Female,
pubmed-meshheading:18221399-Genetic Linkage,
pubmed-meshheading:18221399-Glucocorticoids,
pubmed-meshheading:18221399-Hormone Replacement Therapy,
pubmed-meshheading:18221399-Human Growth Hormone,
pubmed-meshheading:18221399-Humans,
pubmed-meshheading:18221399-Hypertriglyceridemia,
pubmed-meshheading:18221399-Hypopituitarism,
pubmed-meshheading:18221399-Male,
pubmed-meshheading:18221399-Metabolic Syndrome X,
pubmed-meshheading:18221399-Middle Aged,
pubmed-meshheading:18221399-Polymorphism, Single Nucleotide,
pubmed-meshheading:18221399-Prevalence,
pubmed-meshheading:18221399-Promoter Regions, Genetic,
pubmed-meshheading:18221399-Young Adult
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pubmed:year |
2008
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pubmed:articleTitle |
Glucocorticoid replacement is associated with hypertriglyceridaemia, elevated glucose and higher non-HDL cholesterol and may diminish the association of HDL cholesterol with the -629C>A CETP promoter polymorphism in GH-receiving hypopituitary patients.
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pubmed:affiliation |
Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands. r.p.f.dullaart@int.umcg.nl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Evaluation Studies
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