Linked Life Data

18219484

Source:http://linkedlifedata.com/resource/pubmed/id/18219484

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-3-20
pubmed:abstractText
INTRODUCTION: Molecular imaging aims towards the non-invasive characterization of disease-specific molecular alterations in the living organism in vivo. In that, molecular imaging opens a new dimension in our understanding of disease pathogenesis, as it allows the non-invasive determination of the dynamics of changes on the molecular level. IMAGING OF AD CHARACTERISTIC CHANGES BY microPET: The imaging technology being employed includes magnetic resonance imaging (MRI) and nuclear imaging as well as optical-based imaging technologies. These imaging modalities are employed together or alone for disease phenotyping, development of imaging-guided therapeutic strategies and in basic and translational research. In this study, we review recent investigations employing positron emission tomography and MRI for phenotyping mouse models of Alzheimer's disease by imaging. We demonstrate that imaging has an important role in the characterization of mouse models of neurodegenerative diseases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1619-7070
pubmed:author
pubmed:issnType
Print
pubmed:volume
35 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S107-13
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Imaging noradrenergic influence on amyloid pathology in mouse models of Alzheimer's disease.
pubmed:affiliation
Laboratory for Gene Therapy and Molecular Imaging, Max Planck Institute for Neurological Research, and the Faculty of Medicine, University of Cologne, Gleuelerstrasse 50, Cologne, Germany.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't