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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-24
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pubmed:abstractText |
CYP3A metabolizes 50% of currently prescribed drugs and is frequently involved in clinically relevant drug interactions. The understanding of roles and regulations of the individual CYP3A genes in pharmacology and physiology is incomplete.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1744-6872
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
53-66
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pubmed:meshHeading |
pubmed-meshheading:18216722-Animals,
pubmed-meshheading:18216722-Base Sequence,
pubmed-meshheading:18216722-Catalysis,
pubmed-meshheading:18216722-Cytochrome P-450 Enzyme System,
pubmed-meshheading:18216722-DNA, Complementary,
pubmed-meshheading:18216722-Genomics,
pubmed-meshheading:18216722-Humans,
pubmed-meshheading:18216722-Isoenzymes,
pubmed-meshheading:18216722-Molecular Sequence Data,
pubmed-meshheading:18216722-Sequence Homology, Nucleic Acid,
pubmed-meshheading:18216722-Species Specificity
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pubmed:year |
2008
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|
pubmed:articleTitle |
CYP3 phylogenomics: evidence for positive selection of CYP3A4 and CYP3A7.
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pubmed:affiliation |
Department of Pharmacology, Johannes Gutenberg University Mainz, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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