Linked Life Data

18215012

Source:http://linkedlifedata.com/resource/pubmed/id/18215012

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-2-7
pubmed:abstractText
Efficient drug delivery is essential for many therapeutic applications. Some cell-penetrating peptides, peptide mimetics, and peptoids express transport function that, however, lack in most cases specific intracellular destination. In this study, carrier-peptoids with either amino or guanidinium side chains, were investigated with regard to their cellular uptake, toxicity, and intracellular localization. Transport specifically to the cytosol or to the nuclei was observed, thus providing a powerful tool for targeted drug delivery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-2623
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
376-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Peptoidic amino- and guanidinium-carrier systems: targeted drug delivery into the cell cytosol or the nucleus.
pubmed:affiliation
University of Karlsruhe (TH), Institute of Organic Chemistry, Fritz-Haber-Weg 6, Karlsruhe, Germany. braese@ioc.uka.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't