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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-24
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pubmed:abstractText |
The purpose of this review is to present an overview of the state-of-the-art imaging modalities used to track drug delivery from liposomal formulations into tumors during or after hyperthermia treatment. Liposomes are a drug delivery system comprised of a phospholipid bilayer surrounding an aqueous core and have been shown to accumulate following hyperthermia therapy. Use of contrast-containing liposomes in conjunction with hyperthermia therapy holds great promise to be able to directly measure drug dose concentrations as well as to non-invasively describe patterns of drug distribution with MR and PET/SPECT imaging modalities. We will review the rationale for using this approach and the potential advantages of having such information available during and after treatment.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-10519688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-10999769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-11131055,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-11156395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-11228577,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-11306483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-12269857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-15065240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-15170835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-15172159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-15486198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-15675664,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-15675672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16147441,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16161081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16197944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16216216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16754340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16754347,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16818699,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-16902986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17029236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17121901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17202113,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17430630,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17456036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17466462,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-17473205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-2345086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-2394576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-3167010,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-3380005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-364652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-4729825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-631174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-7371678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-8262748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-8557506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18214771-9532526
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0265-6736
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-90
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pubmed:dateRevised |
2010-9-22
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pubmed:meshHeading |
pubmed-meshheading:18214771-Animals,
pubmed-meshheading:18214771-Antineoplastic Agents,
pubmed-meshheading:18214771-Humans,
pubmed-meshheading:18214771-Hyperthermia, Induced,
pubmed-meshheading:18214771-Liposomes,
pubmed-meshheading:18214771-Magnetic Resonance Imaging,
pubmed-meshheading:18214771-Nanoparticles,
pubmed-meshheading:18214771-Neoplasms,
pubmed-meshheading:18214771-Rats,
pubmed-meshheading:18214771-Tissue Distribution,
pubmed-meshheading:18214771-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
2008
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pubmed:articleTitle |
Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques.
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pubmed:affiliation |
Department of Radiation Oncology, Duke University, Durham, NC 27710, USA.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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