CD44 is an essential surface glycoprotein component of the hyaluronan receptor and is associated with adhesion and metastasis in many solid tumors. There are several isoforms of CD44, including CD44 standard (CD44s) and 10 CD44 variants (CD44v1 to CD44v10). We evaluated the clinical significance of CD44s and CD44v6 in biliary tract cancers.
Division of Hematology-Oncology, Department of Internal Medicine, School of Medicine, Ewha Medical Research Center, Ewha Womans University, Mock-Dong 911-1, Yangchun-ku, Seoul, 158-710, Korea.