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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-8-18
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pubmed:abstractText |
This study examines the extent to which 2 mg nicotine gum reduces the prevalence and severity of cigarette withdrawal signs and symptoms. The sample was comprised of women who were randomly assigned to chew 2 mg nicotine gum (N = 206) or no nicotine gum (N = 211). Signs and symptoms of withdrawal were assessed at days 2, 7, 14, and 28 post-cessation. The results showed a significant effect of 2 mg nicotine compared to no gum at 2 days post-cessation on the prevalence of the following symptoms: anxious/tense, difficulty concentrating, restless, impatient, somatic symptoms, insomnia, increased eating, and drowsiness. There were additional differences between the two groups for the severity of craving for cigarettes, irritable/angry, excessive hunger, and total withdrawal score. Over the course of 28 days post-cessation, significant Group and/or Group x Time interaction effects were found with regard to the severity of signs and symptoms for the following variables: impatient, insomnia, increased eating, irritable, difficulty concentrating, restless, somatic complaints, and total withdrawal score. These results are similar to those obtained from placebo-controlled trials for nicotine gum.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0899-3289
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-40
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1821296-Adult,
pubmed-meshheading:1821296-Behavior Therapy,
pubmed-meshheading:1821296-Chewing Gum,
pubmed-meshheading:1821296-Combined Modality Therapy,
pubmed-meshheading:1821296-Energy Intake,
pubmed-meshheading:1821296-Female,
pubmed-meshheading:1821296-Humans,
pubmed-meshheading:1821296-Neurologic Examination,
pubmed-meshheading:1821296-Nicotine,
pubmed-meshheading:1821296-Smoking Cessation,
pubmed-meshheading:1821296-Substance Withdrawal Syndrome
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pubmed:year |
1991
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pubmed:articleTitle |
Effects of nicotine gum on prevalence and severity of withdrawal in female cigarette smokers.
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pubmed:affiliation |
Department of Psychiatry, University of Minnesota, Minneapolis 55455.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
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