Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-8-18
pubmed:abstractText
This study examines the extent to which 2 mg nicotine gum reduces the prevalence and severity of cigarette withdrawal signs and symptoms. The sample was comprised of women who were randomly assigned to chew 2 mg nicotine gum (N = 206) or no nicotine gum (N = 211). Signs and symptoms of withdrawal were assessed at days 2, 7, 14, and 28 post-cessation. The results showed a significant effect of 2 mg nicotine compared to no gum at 2 days post-cessation on the prevalence of the following symptoms: anxious/tense, difficulty concentrating, restless, impatient, somatic symptoms, insomnia, increased eating, and drowsiness. There were additional differences between the two groups for the severity of craving for cigarettes, irritable/angry, excessive hunger, and total withdrawal score. Over the course of 28 days post-cessation, significant Group and/or Group x Time interaction effects were found with regard to the severity of signs and symptoms for the following variables: impatient, insomnia, increased eating, irritable, difficulty concentrating, restless, somatic complaints, and total withdrawal score. These results are similar to those obtained from placebo-controlled trials for nicotine gum.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0899-3289
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
427-40
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Effects of nicotine gum on prevalence and severity of withdrawal in female cigarette smokers.
pubmed:affiliation
Department of Psychiatry, University of Minnesota, Minneapolis 55455.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial