Linked Life Data

1820693

Source:http://linkedlifedata.com/resource/pubmed/id/1820693

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-8-3
pubmed:abstractText
The role of Sucralfate in prevention of acute gastric injuries and its comparison with free radicals blockers as Allopurinol, Soybean Trypsin Inhibitor and Superoxide Dismutase was studied in the ischemia-reperfusion model by total occlusion of the celiac axis in Wistar rats. In control rats, the gross gastric mucosal necrotic area was of 80%; in contrast, the antioxidant drugs resulted in a necrotic area of 7%-15% and Sucralfate resulted in a necrotic area of only a 4%. It was concluded that Sucralfate, as antioxidant-cytoprotective drug, by enhancing the gastric defensive barrier was more important than the secondary aggression induced by free radicals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9033
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-8
pubmed:dateRevised
2006-12-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Sucralfate in the prevention of acute gastric lesions induced by ischemia-reperfusion.
pubmed:affiliation
Cathedra of Medical Pathology III (Gastroenterology), Faculty of Medicine, Rosario, Argentine.
pubmed:publicationType
Journal Article, Comparative Study