rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2008-2-15
|
pubmed:abstractText |
Cutaneous malignant melanoma is an aggressive type of skin cancer which causes disproportionate mortality in young and middle-aged adults. Once disseminated, melanoma can be considered an incurable disease, highly resistant to standard antineoplastic treatment, such as chemotherapy or radiation therapy. The proteasome represents a novel target for cancer therapy that can potentially be used in melanoma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0007-0963
|
pubmed:author |
pubmed-author:CasanovaJ MJM,
pubmed-author:DolcetXX,
pubmed-author:EgidoRR,
pubmed-author:LlobetDD,
pubmed-author:LlombartAA,
pubmed-author:MartiR MRM,
pubmed-author:Matias-GuiuXX,
pubmed-author:Pérez de SantosA MAM,
pubmed-author:SchoenenbergerJ AJA,
pubmed-author:SmithG NGN,
pubmed-author:SorollaAA,
pubmed-author:VilellaRR,
pubmed-author:YeramianAA
|
pubmed:issnType |
Print
|
pubmed:volume |
158
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
496-504
|
pubmed:meshHeading |
pubmed-meshheading:18205878-Apoptosis,
pubmed-meshheading:18205878-Boronic Acids,
pubmed-meshheading:18205878-Cell Death,
pubmed-meshheading:18205878-Cell Line, Tumor,
pubmed-meshheading:18205878-Cell Proliferation,
pubmed-meshheading:18205878-Drug Resistance, Multiple,
pubmed-meshheading:18205878-Female,
pubmed-meshheading:18205878-Humans,
pubmed-meshheading:18205878-Male,
pubmed-meshheading:18205878-Melanoma,
pubmed-meshheading:18205878-Protease Inhibitors,
pubmed-meshheading:18205878-Pyrazines,
pubmed-meshheading:18205878-Skin Neoplasms,
pubmed-meshheading:18205878-Treatment Outcome
|
pubmed:year |
2008
|
pubmed:articleTitle |
Effect of proteasome inhibitors on proliferation and apoptosis of human cutaneous melanoma-derived cell lines.
|
pubmed:affiliation |
Department of Dermatology, and Laboratory of Research, Hospital Universitair Arnau de Vilanova, Universitat de Lleida, 25198 Lleida, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|