Linked Life Data

18205477

Source:http://linkedlifedata.com/resource/pubmed/id/18205477

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-1-21
pubmed:abstractText
Preferential affinity of cholesterol for saturated rather than unsaturated lipids underlies the thermodynamic process of the formation of lipid nanostructures in cell membranes, that is, of rafts. In this context, phase segregation of two-dimensional ternary lipid mixtures is formally studied from two different perspectives. The simplest approach is based on Monte Carlo simulations of an Ising model corresponding to two interconnected lattices, from which the basic features of the phenomenon are investigated. Then, the coarse-graining mean field procedure of the discrete Hamiltonian is adapted and a Ginzburg-Landau-like free energy expression is obtained. From this latter description, we construct kinetic equations that enable us to perform numerical simulations and to establish analytical phase separation criteria. Application of our formalism in the biological context is also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0021-9606
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
025102
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Phase separation in three-component lipid membranes: from Monte Carlo simulations to Ginzburg-Landau equations.
pubmed:affiliation
Departament de Química-Física, Universitat de Barcelona, Avda. Diagonal 647, 08028 Barcelona, Spain. reigada@ub.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't