Source:http://linkedlifedata.com/resource/pubmed/id/18205378
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-2-11
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pubmed:abstractText |
A stereoselective and efficient total synthesis of optically active tetrodotoxin (TTX) is described. A polyfunctionalized key cyclitol compound containing branched-chains for the synthesis of TTX was prepared from D-glucose employing the Henry reaction (Nitro aldol reaction) as the key transformation. Stereoselective construction of the alpha-azido-aldehyde branched-chain was achieved via the key spiro alpha-chloroepoxide intermediate.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-3263
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pubmed:author |
pubmed-author:AkaiShojiS,
pubmed-author:FunabashiMasuoM,
pubmed-author:KajiharaYasuhiroY,
pubmed-author:NagaiYoshinaoY,
pubmed-author:NakamuraYutakaY,
pubmed-author:SatoKen-ichiK,
pubmed-author:ShojiHirotsuguH,
pubmed-author:SugitaNaokiN,
pubmed-author:SuzukiKatsuhikoK,
pubmed-author:YoshidaShihoS,
pubmed-author:YoshimuraJujiJ
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1234-42
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pubmed:meshHeading | |
pubmed:year |
2008
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pubmed:articleTitle |
Stereoselective and efficient total synthesis of optically active tetrodotoxin from D-glucose.
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pubmed:affiliation |
Department of Applied Chemistry, Faculty of Engineering, Kanagawa University, Yokohama, 221-8686, Japan. satouk01@kanagawa-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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