Source:http://linkedlifedata.com/resource/pubmed/id/18202421
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2008-1-18
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pubmed:abstractText |
Tumor shrinkage categorized as complete response (CR) or partial response (PR) is a fundamental efficacy measure for new cancer treatments and often considered a surrogate for overall survival. However, for any given treatment, many more patients typically achieve stable disease (SD) or have progressive disease (PD) than achieve response. We hypothesized that PD (or its converse, disease control rate [DCR], consisting of CR, PR, SD) is a stronger predictor of survival than response alone in advanced non-small-cell lung cancer (NSCLC), and that this determination might be assessable early on during therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1527-7755
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
463-7
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pubmed:meshHeading |
pubmed-meshheading:18202421-Aged,
pubmed-meshheading:18202421-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18202421-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:18202421-Control Groups,
pubmed-meshheading:18202421-Female,
pubmed-meshheading:18202421-Humans,
pubmed-meshheading:18202421-Lung Neoplasms,
pubmed-meshheading:18202421-Male,
pubmed-meshheading:18202421-Middle Aged,
pubmed-meshheading:18202421-Prognosis,
pubmed-meshheading:18202421-Remission Induction,
pubmed-meshheading:18202421-Survival Rate,
pubmed-meshheading:18202421-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Disease control rate at 8 weeks predicts clinical benefit in advanced non-small-cell lung cancer: results from Southwest Oncology Group randomized trials.
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pubmed:affiliation |
University of California Davis Cancer Center, 4501 X St, Sacramento, CA 95817, USA. primo.lara@ucdmc.ucdavis.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial
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